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Senokot Constipation Relief Syrup - 150 ml

£9.9£99Clearance
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This medicine contains 0.09 mmol (or 3.51 mg) potassium per 5 ml. To be taken into consideration by patients with reduced kidney function or patients on a controlled potassium diet.

If you forget a dose of senna, just skip the missed dose and take the next dose the following evening. There was no evidence of any embryolethal, teratogenic or foetotoxic actions in rats or rabbits after oral treatment with sennosides. Furthermore, there was no effect on the postnatal development of young rats, on rearing behaviour of dams or on male and female fertility in rats. Data for herbal preparations are not available. Duration of use: Normally it is sufficient to take this medicinal product two to three times a week. Use for more than 1 –2 weeks requires medical supervision. Tell a doctor, pharmacist or nurse if: – the symptoms worsen or persist during the use of the medicinal product – there is no bowel movement within 3 days ofuse – you need to take laxatives every day or if abdominal pain persists.If no bowel action has occurred after three days of progressively increased dosage, a medical examination should be considered.

Patients taking cardiac glycosides, antiarrhythmic medicinal products, medicinal products inducing QT-prolongation, diuretics, adrenocorticosteroids or liquorice root, have to consult a doctor before taking senna leaf preparation concomitantly. Only give senna that you buy to a young person aged 12 to 17 years if a doctor or pharmacist recommends it. Dosage for senna tablets prescribed by a doctor The sugar moiety of the sennosides is removed by bacteria in the large intestine releasing the active anthrone fraction. This stimulates peristalsis via the submucosal and myenteric nerve plexuses. New users should start the lowest dose and increase, to the maximum dose for each age group, if necessary, by one half of the initial dose each day. Once regularity has been regained the dosage should be reduced and can usually be stopped.Chronic use may cause pigmentation of the intestinal mucosa (pseudomelanosis coli), which usually recedes when the patient stops taking the preparation.

Intestinal loss of fluids may promote dehydration. Symptoms may include thirst and oliguria. In patients suffering from fluid loss where dehydration may be harmful (e.g.renal insufficiency, elderly patients) Senokot Syrup Pharmacy should be discontinued and only be restarted under medical supervision. If you are still constipated after taking senna for 3 days, talk to your doctor. If you forget to take it Senokot tablets, syrup and granules contain Senna, a natural plant extract which works by stimulating the muscles in the bowel in a similar way to figs and prunes. Helping to bring gentle, predictable relief. Senokot works with your body, leaving you feeling much fresher and brighter again. There are no new, systematic preclinical tests for senna leaves or preparations thereof. Data derive from investigations with senna pods. Since the spectrum of constituents of senna leaf and fruit is comparable these data can be transferred to senna leaves. Most data refer to extracts of senna pods containing 1.4 to 3.5% of anthranoids, corresponding to 0.9 to 2.3% of potential rhein, 0.05 to 0.15% of potential aloe-emodin and 0.001 to 0.006% of potential emodin or isolated active constituents, e.g. rhein or sennosides A and B. The acute toxicity of senna pods, specified extracts thereof, as well as of sennosides in rats and mice was low after oral treatment. Often, increasing the amount of fibre in your diet (such as by eating more fruit, vegetables, cereals, and wholemeal bread) and drinking plenty of water each day can effectively prevent or relieve constipation.

the guidance of a medical professional. Do not exceed the stated dose Senokot 7.5mg/5ml Syrup usually works in 8–12 hours. New users should start with the lowest dose and if needed increase by half the initial dose each day. When you feel the medicine is working, gradually reduce the dose and stop. In addition a specified senna extract given orally for 2 years was not carcinogenic in male or female rats. The extract investigated contained approximately 40.8% of anthranoids from which 35% were sennosides, corresponding to about 25.2% of potential rhein, 2.3% of potential aloe-emodin and 0.007% of potential emodin and 142 ppm free aloe-emodin and 9 ppm free emodin. influence on secretion processes by two concomitant mechanisms viz. inhibition of absorption of water and electrolytes (Na+, Cl-) into the colonic epithelial cells (antiabsorptive effect) and increase of the leakiness of the tight junctions and stimulation of secretion of water and electrolytes into the lumen of the colon (secretagogue effect) resulting in enhanced concentrations of fluid and electrolytes in the lumen of the colon. Duration of use: Normally it is sufficient to take this medicinal product two to three times a week. Use for more than 1 –2 weeks requires medical supervision. Tell a doctor, pharmacist or nurse if: – the symptoms worsen or persist during the use of the medicinal product – there is no bowel movement within 3 days of use dihydroxyanthracene derivatives possess a laxative effect. The β-Ο-linked glycosides (sennosides) are not absorbed in the upper gut; they are converted by bacteria of the large intestine into the active metabolite (rhein anthrone).

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